U Destru is the macro-neighborhood that occupies a large part of the slope that descends from the ridge (Corso Umberto I) towards the small river of Provvidenza. The toponym, rather than indicating the right side of the town facing the sea, signifies that part of the town always exposed to the great gift of the regenerating warmth of the sun throughout all four seasons of the year.

As it is located on less resistant terrain, it is more prone to the risk of urban instability due to adverse weather conditions, as happened with the flood of October 1951.

Today, only a few people reside there, but in the past, the neighborhood was densely populated. Perhaps due to the sun, which generally encourages relaxation, rest, and a bit of laziness, the people of Destru have typically engaged in lighter activities than the daily use of the heavy hoe. Farmers still prevailed there, like most of the town, but they preferred lighter agricultural activities. There were numerous artisans, surpassed only in percentage by Via Vittorio Emanuele III, where, within a few hundred meters, from the Arco del Girone to the Church of Saint Nicholas, there were four carpenters, two coopers, a shoemaker, a blacksmith, and a tinsmith. In the neighborhood, there was a Badolato craftswoman who transformed silk cocoons into thread ready for weaving.

Today, U Destru is slowly and laboriously repopulating, with people arriving from outside, purchasing even dilapidated houses, restoring them, and living there, some intermittently and others permanently.